Best Cruises to Italy From the USA

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Set sail across the vast Atlantic to the Old World on one of our cruises to Italy from the USA. Enjoy the blissful days communing with the sea, enjoying fine dining, and relaxing by the pool as you head from Fort Lauderdale to ports in Portugal, Spain, France, and Italy.

Embark in Ft. Lauderdale, Florida, and head for the volcanic Azores, a mid-Atlantic archipelago that combines colonial charm with lush, mountainous scenery. Pass through the narrow Straits of Gibraltar, the entrance to the sparkling Mediterranean. Trace the coastline of the Iberian peninsula and the glamorous Côte d’Azur in France before heading along Italy’s glorious west coast and disembarking in Rome.

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See Cruises to Italy from the U.S.

Featured Ports of Call

Rome

A cruise to Italy from the U.S. ends in Rome, where you’ll find a captivating combination of historic buildings, art treasures, and beautiful squares set around splashing fountains. Learn about gladiatorial battles in the mighty Colosseum before heading to laid-back Trastevere for a cappuccino and a tour of the baroque Palazzo San Callisto. Don’t miss the Vatican Museums and the Sistine Chapel, where you’ll see priceless works by Bernini, Caravaggio, Raphael, and Michelangelo.

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Ponta Delgada

Ponta Delgada, the enchanting capital of the volcanic Azores archipelago, is the gateway to lush landscapes of hot springs, waterfalls, verdant mountains, and blue-green lakes reflecting vast skies. This is also one of the most exciting spots in the world for whale-watching trips. The city itself is a delight, packed with 16th- and 17th-century architecture, elegant baroque churches, pretty squares, and enticing restaurants where you can feast on fresh Atlantic seafood and island wines.

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Barcelona

Culture, shopping, beaches, and gastronomy—buzzing Barcelona has it all. Lose yourself in the shaded alleys of the old Gothic Quarter, or watch captivating street entertainers along Las Ramblas boulevard. Marvel at the Picasso Museum, housing more than 4,000 pieces of the artist’s work. Browse the mouthwatering stalls in La Boqueria market, and head to Barceloneta for tapas on the beach. Visit La Sagrada Familia, Antoni Gaudi’s extraordinary basilica, which dominates the Eixample neighborhood.

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